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Ferric C. Fang, MD

“The universality of the deep chemistry of living things is indeed a fantastic and beautiful thing.”

---Richard Feynman

Department of Laboratory Medicine, NW120 University of Washington, Box 357110 1959 Pacific St. Seattle, WA 98195
(206) 221-6770
Ferric C. Fang, MD
Professor of Laboratory Medicine and Microbiology; Adjunct Professor of Medicine; Director, Clinical Microbiology Laboratory, Harborview Medical Center.

The Fang laboratory studies a broad range of topics in bacterial pathogenesis, with a particular focus on phagocyte-pathogen interactions. Specific projects include the antimicrobial actions of reactive oxygen and nitrogen species in Salmonella enterica and Staphylococcus aureuspathogenesis, iron metabolism in host-pathogen interactions, control of Salmonella virulence gene expression by alternative sigma factors and other transcriptional regulators, and the pathogenesis of human typhoid. Using a genomic approach, the Fang laboratory discovered "xenogeneic silencing," a mechanism by which bacteria recognize and integrate foreign DNA into pre-existing regulatory networks. Professor Fang also oversees the Clinical Microbiology Laboratory of the 413-bed Harborview Medical Center, where he is working on molecular methods for improved diagnosis of bacterial infections.