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Diseases

Diseases studied at CERID.

HIV Research at CERID

HIV Research at CERID is focused on:

Pathogenesis

Genetic Susceptibility

 

Tuberculosis Research at CERID

Tuberculosis Research at CERID is focused on:

Pathogenesis

Immune Response

Vaccine Development

Enteritis

Enteritis refers to inflammation of the small intestine caused by the ingestion of substances contaminated with pathogens. It is commonly referred to as "food poisoning."

Bacteria that cause enteritis are encountered in various Salmonella species. The organism enters through the digestive tract and must be ingested in large numbers to cause disease in healthy adults. Gastric acidity is responsible for the destruction of the majority of ingested bacteria. Bacterial colonies may become trapped in mucus produced in the esophagus.

Helminth Infection

Helminths are a polyphyletic group of parasitic worms, eukaryotic parasites that live in and feed on living hosts. They receive nourishment and protection while disrupting their hosts' nutrient absorption, causing weakness and disease. 

Merkel Cell Carcinoma

Merkel cell carcinoma is a very rare and aggressive skin cancer typically caused by the Merkel cell polyomavirus. It was discovered by scientists at the University of Pittsburgh in 2008. MCM is also known as primary neuroendocrine carcinoma of the skin or trabecular cancer.

Neosporosis

Neospora caninum is a microscopic protozoan parasite with worldwide distribution. Many domestic (dogs, cattle, sheep, goats, horses, chickens) and wild animals (deer, rodents, rabbits, coyotes, wolves, foxes) can be infected. Neosporosis is one of the most common causes of bovine abortion, especially in intensively farmed cows. Neosporosis abortion also occurs in sheep, goats, water buffalo and South American camelids, although they may be less susceptible than cattle.

Newcastle Disease

Newcastle disease virus (NDV) - A type strain for avian paramyxoviruses. Members of this family have a single stranded, linear, RNA, with an elliptical symmetry. NDV is a contagious and fatal viral disease affecting most species of birds. Clinical signs are extremely variable depending on the strain of virus, species and age of bird, concurrent disease, and preexisting immunity.

Toxoplasmosis

Toxoplasmosis is a parasitic disease caused by the protozoan Toxoplasma gondii. The parasite infects most warm-blooded animals. The primary host is the felid (cat) family. Animals are infected by eating infected meat, by ingestion of feces of a cat that has itself recently been infected, and by transmission from mother to fetus. Cats are the primary source of infection to human hosts, although contact with raw meat, especially lamb, is a more significant source of human infections in some countries. Fecal contamination of hands is a significant risk factor.

Smallpox

Smallpox is an infectious disease caused by the Variola virus that was succesfully eradicated in 1979. The disease is also known by the Latin names Variola or Variola vera, derived from varius ("spotted") or varus ("pimple"). The disease was originally known in English as the "pox" or "red plague"; the term "smallpox" was first used in Britain in the 15th century to distinguish variola from the "great pox" (syphilis). The last naturally occurring case of smallpox (Variola minor) was diagnosed in Somalia on 26 October 1977.

Staph Infections

Staphylococcus is a genus of Gram-positive bacteria. Under the microscope, they appear round (cocci), and form in grape-like clusters.

The Staphylococcus genus includes at least 30 species. Most are harmless and reside normally on the skin and mucous membranes of humans and other organisms. Found worldwide, they are a small component of soil microbial flora.

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