Frederick S. Buckner, MD | Center for Emerging and Re-emerging Infectious Diseases

Professor

Department of Medicine, Division of Allergy and Infectious Diseases

Faculty Information

Biography

Dr. Buckner's research is focused on the discovery of antimicrobial agents, including antiparasitic and antibacterial drugs.

He works in the arena of preclinical research including target identification/validation, compound screening, pharmacology and small-animal efficacy models.

Education & Training:

Princeton University

Princeton NJ

1979-1983

University of Washington

Seattle WA

1984-1988

Intern/Residency

University of Minnesota

Minneapolis, MN

1988-1991

Chief Resident,

Minneapolis Veterans Administration Medical Center

Minneapolis MN

1991-1992

Infectious Diseases Fellowship

University of Washington

Seattle WA

1992-1995

Honors:

Magna Cum Laude, Princeton University

1983

Graduation with Honors, University of Washington Medical School

1988

Philip and Helen Fialkow Scholar, University of Washington

2004

Science in Medicine Lectureship, University of Washington

2012

President, Western Society for Clinical Investigation

2015

Alpha Omega Alpha Honor Medical Society

2018

Contact

Email:

fbuckner@uw.edu

Phone:

(206) 616-9214

Mailing Address:

750 Republican Street, Room E631, Seattle, WA 98109

Publications

PubMed:

PubMed Bibliography

Publications:

Buckner FS, Ranade RM, Gillespie JR, Shibata S, Hulverson MA, Zhang Z, Huang W, Choi R, Verlinde CLMJ, Hol WGJ, Ochida A, Akao Y, Choy RKM, Van Voorhis WC, Arnold SLM, Jumani RS, Huston CD, Fan E. Optimization of Methionyl tRNA-Synthetase Inhibitors for Treatment of Cryptosporidium Infection. Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02061-18. doi: 10.1128/AAC.02061-18. Print 2019 Apr. PubMed PMID: 30745384.

Nagendar P, Gillespie JR, Herbst ZM, Ranade RM, Molasky NMR, Faghih O, Turner RM, Gelb MH, Buckner FS. Triazolopyrimidines and Imidazopyridines: Structure-Activity Relationships and in Vivo Efficacy for Trypanosomiasis. ACS Med Chem Lett. 2018 Dec 4;10(1):105-110. doi: 10.1021/acsmedchemlett.8b00498. eCollection 2019 Jan 10. PubMed PMID: 30655955; PubMed Central PMCID: PMC6331164.

Faghih O, Zhang Z, Ranade RM, Gillespie JR, Creason SA, Huang W, Shibata S, Barros-Álvarez X, Verlinde CLMJ, Hol WGJ, Fan E, Buckner FS. Development of Methionyl-tRNA Synthetase Inhibitors as Antibiotics for Gram-Positive Bacterial Infections. Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e00999-17. doi: 10.1128/AAC.00999-17. Print 2017 Nov. PubMed PMID: 28848016; PubMed Central PMCID: PMC5655057.

Patrick DA, Gillespie JR, McQueen J, Hulverson MA, Ranade RM, Creason SA, Herbst ZM, Gelb MH, Buckner FS, Tidwell RR. Urea Derivatives of 2-Aryl-benzothiazol-5-amines: A New Class of Potential Drugs for Human African Trypanosomiasis. J Med Chem. 2017 Feb 9;60(3):957-971. doi: 10.1021/acs.jmedchem.6b01163. Epub 2016 Dec 19. PubMed PMID: 27992217; PubMed Central PMCID: PMC5362113.