Associate ProfessorDepartment of Medicine, Division of Allergy and Infectious Diseases Adjunct Assistant ProfessorDepartment of Microbiology Adjunct Assistant ProfessorDepartment of Global Health Related Links: Hybiske Lab Hybiske Lab WebsiteFaculty Information Biography Education & Training: PhD, Molecular and Cell BiologyUniversity of CaliforniaBerkeley CA2003 Postdoctoral fellowUniversity of CaliforniaBerkeley CA2003 Postdoctoral fellowUniversity of CaliforniaBerkeley CA2003-2005 Postdoctoral fellowUniversity of CaliforniaBerkeley CA2003-2005 Honors: Predoctoral Fellowship Award, California Tobacco-Related Disease Research Program1999-2002 NIAID Young Investigator Award2010 Top Ten Reviewer for Cellular Microbiology2013 Contact Email: khybiske@uw.eduPhone: (206) 616-1549Mailing Address: 750 Republican Street, Box 358061, Seattle, WA 98109-4725 Research & Clinical Interests Research Interests: The Hybiske Lab investigates the molecular mechanisms of Chlamydia pathogenesis, including sexually transmitted infections. Our ultimate goals are to identify new therapeutic targets against this major pathogen, and to contribute to our broader understanding of the pathogenic mechanisms of intracellular bacteria. Current research projects include: Mechanisms of Chlamydia exit from host cells, dissemination, and immune evasion Functional genomics for Chlamydia Virulence factor discovery for Chlamydia Proteomic discovery of novel Chlamydia-host interactions Publications PubMed: PubMed BibliographyPublications: Chin E, Kirker K, Zuck M, James G, Hybiske K. Actin recruitment to the Chlamydia inclusion is spatiotemporally regulated by a mechanism that requires host and bacterial factors. PLoS ONE. 2012; 7(10): e46949. Hybiske K, Stephens RS. Exit strategies of intracellular pathogens. Nature Reviews Microbiol. 2008; 6: 99-110. Hybiske K, Stephens RS. Mechanisms of host cell exit by the intracellular bacterium Chlamydia. Proc Natl Acad Sci USA. 2007; 104: 11430-11435. Hybiske K, Stephens RS. Entry mechanisms of Chlamydia trachomatis into non-phagocytic cells. Infect Immun. 2007; 75: 3925-3934.
