Lab equipment with a sticker that says Good Ideas Always Filter Through

Get a sense of our research - browse our investigators' and labs' most recent publications.

This is unpublished


Our publication efforts not only demonstrate the variety of infectious disease research we produce as a whole, but the breadth of our collaborations as well. 

CERID PIs highlighted in bold and lab staff are italicized, CERID affiliates are underlined.


Selected works

Comparison of Clinical Features and Outcomes in Critically Ill Patients Hospitalized with COVID-19 versus Influenza.

Cobb NL, Sathe NA, Duan KI, Seitz KP, Thau MR, Sung CC MD, Morrell ED, Mikacenic C, Kim HN, Liles WC, Luks AM, Town J, Pipavath S, Wurfel MM, Hough CL, West TE, Bhatraju PK.

Ann Am Thorac Soc. 2020 Nov 13. doi: 10.1513/AnnalsATS.202007-805OC. Online ahead of print.

PMID: 33183067

De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2.

Linsky TW, Vergara R, Codina N, Nelson JW, Walker MJ, Su W, Barnes CO, Hsiang TY, Esser-Nobis K, Yu K, Reneer ZB, Hou YJ, Priya T, Mitsumoto M, Pong A, Lau UY, Mason ML, Chen J, Chen A, Berrocal T, Peng H, Clairmont NS, Castellanos J, Lin YR, Josephson-Day A, Baric RS, Fuller DH, Walkey CD, Ross TM, Swanson R, Bjorkman PJ, Gale M Jr, Blancas-Mejia LM, Yen HL, Silva DA.

Science. 2020 Nov 5:eabe0075. doi: 10.1126/science.abe0075. Online ahead of print.

PMID: 33154107

Human Metapneumovirus Infection and Genotyping of Infants in Rural Nepal.

Perchetti GA, Wilcox N, Chu HY, Katz J, Khatry SK, LeClerq SC, Tielsch JM, Jerome KR, Englund JA, Kuypers J.

J Pediatric Infect Dis Soc. 2020 Nov 2:piaa118. doi: 10.1093/jpids/piaa118. Online ahead of print.

PMID: 33137178

Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2.


Walls AC, Fiala B, Schäfer A, Wrenn S, Pham MN, Murphy M, Tse LV, Shehata L, O'Connor MA, Chen C, Navarro MJ, Miranda MC, Pettie D, Ravichandran R, Kraft JC, Ogohara C, Palser A, Chalk S, Lee EC, Guerriero K, Kepl E, Chow CM, Sydeman C, Hodge EA, Brown B, Fuller JT, Dinnon KH 3rd, Gralinski LE, Leist SR, Gully KL, Lewis TB, Guttman M, Chu HY, Lee KK, Fuller DH, Baric RS, Kellam P, Carter L, Pepper M, Sheahan TP, Veesler D, King NP.


Cell. 2020 Oct 31:S0092-8674(20)31450-1. doi: 10.1016/j.cell.2020.10.043. Online ahead of print.


PMID: 33160446 Free PMC article.

Risk Factors for testing positive for SARS-CoV-2 in a national US healthcare system.


Fan VS, Dominitz JA, Eastment MC, Locke E, Green P, Berry K, O'Hare AM, Shah JA, Crothers K, Ioannou GN.


Clin Infect Dis. 2020 Oct 27:ciaa1624. doi: 10.1093/cid/ciaa1624. Online ahead of print.


PMID: 33105485

Synthesis and structure-activity relationships of imidazopyridine/pyrimidine- and furopyridine-based anti-infective agents against trypanosomiases.


Silva DG, Junker A, de Melo SMG, Fumagalli F, Gillespie JRMolasky N, Buckner FS, Matheeussen A, Caljon G, Maes L, Emery FS.


ChemMedChem. 2020 Oct 19. doi: 10.1002/cmdc.202000616. Online ahead of print.


PMID: 33078573

HIV-2 Drug Resistance Genotyping from Dried Blood Spots.


Raugi DN, Nixon RS, Leong S, Faye KDiatta JPSall FSmith RASall EIMalomar JJSeydi MGottlieb GS; University of Washington-Senegal HIV-2 Research Group.


J Clin Microbiol. 2020 Oct 14:JCM.02303-20. doi: 10.1128/JCM.02303-20. Online ahead of print.


PMID: 33055182

Cytokines 2020 Virtual Meeting.

Gale M , Jr, Savan R.


J Interferon Cytokine Res. 2020 Oct 14. doi: 10.1089/jir.2020.29019.mga. Online ahead of print.


PMID: 33052713 No abstract available.

Clinical, laboratory, and temporal predictors of neutralizing antibodies to SARS-CoV-2 after COVID-19.

Boonyaratanakornkit J, Morishima C, Selke S, Zamora D, McGuffin S, Shapiro AE, Campbell VLMcClurkan CLJing L, Gross R, Liang J, Postnikova E, Mazur S, Chaudhary A, Das MK, Fink SL, Bryan A, Greninger AL, Jerome KR, Holbrook MR, Gernsheimer TB, Wener MH, Wald A, Koelle DM.


medRxiv. 2020 Oct 8:2020.10.06.20207472. doi: 10.1101/2020.10.06.20207472. Preprint.


PMID: 33052361 Free PMC article.

The Seattle Flu Study: a multiarm community-based prospective study protocol for assessing influenza prevalence, transmission and genomic epidemiology.

Chu HY, Boeckh M, Englund JA, Famulare M, Lutz B, Nickerson DA, Rieder M, Starita LM, Adler A, Brandstetter E, Frazer CD, Han PD, Gulati RK, Hadfield J, Jackson M, Kiavand A, Kimball LE, Lacombe K, Newman K, Sibley TR, Logue JK, Lyon VR, Wolf CR, Zigman Suchsland M, Shendure J, Bedford T.


BMJ Open. 2020 Oct 7;10(10):e037295. doi: 10.1136/bmjopen-2020-037295.


PMID: 33033018 Free PMC article.

New horizons in adjuvants for vaccine development.


Reed SG, Tomai M, Gale MJ Jr.


Curr Opin Immunol. 2020 Oct 7;65:97-101. doi: 10.1016/j.coi.2020.08.008. Online ahead of print.


PMID: 33038865

Dynamics of neutralizing antibody titers in the months after SARS-CoV-2 infection.

Crawford KHD, Dingens AS, Eguia R, Wolf CR, Wilcox N, Logue JK, Shuey K, Casto AM, Fiala B, Wrenn S, Pettie D, King NP, Greninger AL, Chu HY, Bloom JD.


J Infect Dis. 2020 Sep 30:jiaa618. doi: 10.1093/infdis/jiaa618. Online ahead of print.


PMID: 33000143

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity.

Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN, Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li J, Khatri A, Chu HY; MGH COVID-19 Collection & Processing Team, Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ.


Science. 2020 Sep 29:eabd4250. doi: 10.1126/science.abd4250. Online ahead of print.


PMID: 32994364

Characteristics of COVID-19 in Homeless Shelters : A Community-Based Surveillance Study.


Rogers JH, Link AC, McCulloch D, Brandstetter E, Newman KL, Jackson ML, Hughes JP, Englund JA, Boeckh M, Sugg N, Ilcisin M, Sibley TR, Fay K, Lee J, Han P, Truong M, Richardson M, Nickerson DA, Starita LM, Bedford T, Chu HY.


Ann Intern Med. 2020 Sep 15. doi: 10.7326/M20-3799. Online ahead of print.


PMID: 32931328

Cryptic transmission of SARS-CoV-2 in Washington state.

Bedford T, Greninger AL, Roychoudhury P, Starita LM, Famulare M, Huang ML, Nalla A, Pepper G, Reinhardt A, Xie H, Shrestha L, Nguyen TN, Adler A, Brandstetter E, Cho S, Giroux D, Han PD, Fay K, Frazar CD, Ilcisin M, Lacombe K, Lee J, Kiavand A, Richardson M, Sibley TR, Truong M, Wolf CR, Nickerson DA, Rieder MJ, Englund JA; Seattle Flu Study Investigators, Hadfield J, Hodcroft EB, Huddleston J, Moncla LH, Müller NF, Neher RA, Deng X, Gu W, Federman S, Chiu C, Duchin JS, Gautom R, Melly G, Hiatt B, Dykema P, Lindquist S, Queen K, Tao Y, Uehara A, Tong S, MacCannell D, Armstrong GL, Baird GS, Chu HY, Shendure J, Jerome KR.


Science. 2020 Sep 10:eabc0523. doi: 10.1126/science.abc0523. Online ahead of print.


PMID: 32913002

Risk Factors for Hospitalization, Mechanical Ventilation, or Death Among 10 131 US Veterans With SARS-CoV-2 Infection.

Ioannou GN, Locke E, Green P, Berry K, O'Hare AM, Shah JA, Crothers K, Eastment MC, Dominitz JA, Fan VS.


JAMA Netw Open. 2020 Sep 1;3(9):e2022310. doi: 10.1001/jamanetworkopen.2020.22310.


PMID: 32965502

Cross-Sectional Prevalence of SARS-CoV-2 Among Skilled Nursing Facility Employees and Residents Across Facilities in Seattle.


Weil AA, Newman KL, Ong TD, Davidson GH, Logue J, Brandstetter E, Magedson A, McDonald D, McCulloch DJ, Neme S, Lewis J, Duchin JS, Zhong W, Starita LM, Bedford T, Roxby AC, Chu HY.


J Gen Intern Med. 2020 Sep 1. doi: 10.1007/s11606-020-06165-7. Online ahead of print.


PMID: 32875494

Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models.


Shears MJ, Seilie AM, Kim Lee Sim B, Hoffman SL, Murphy SC.


Malar J. 2020 Aug 31;19(1):313. doi: 10.1186/s12936-020-03385-4.


PMID: 32867784

Reduced treatment frequencies with bumped kinase inhibitor 1369 are effective against porcine cystoisosporosis.

Shrestha A, Ruttkowski B, Greber P, Whitman GRHulverson MAChoi RMichaels SAOjo KKVan Voorhis WC, Joachim A.


Int J Parasitol Drugs Drug Resist. 2020 Aug 21;14:37-45. doi: 10.1016/j.ijpddr.2020.08.005. Online ahead of print.


PMID: 32861205

Case 27-2020: A 53-Year-Old Woman with Headache and Gait Imbalance.


Gottlieb GS, Rosenberg JM, Gonzalez RG, Gandhi RT.


N Engl J Med. 2020 Aug 27;383(9):859-866. doi: 10.1056/NEJMcpc1913472.


PMID: 32846066

Uptake, retention, and outcomes in a demonstration project of pre-exposure prophylaxis among female sex workers in public health centers in Senegal.

Sarr M, Gueye D, Mboup A, Diouf O, Bao MDB, Ndiaye AJ, Ndiaye BP, Hawes SE, Tousset E, Diallo A, Jones F, Kane CT, Thiam S, Ndour CT, Gottlieb GS, Mboup S.


Int J STD AIDS. 2020 Aug 20:956462420943704. doi: 10.1177/0956462420943704. Online ahead of print.


PMID: 32819210


A Modular Microscale Granuloma Model for Immune-Microenvironment Signaling Studies in vitro.


Berry SB, Gower MS, Su X, Seshadri C, Theberge AB.


Front Bioeng Biotechnol. 2020 Aug 18;8:931. doi: 10.3389/fbioe.2020.00931. eCollection 2020.


PMID: 32974300 Free PMC article.

CFTR Modulator Therapy Enhances Peripheral Blood Monocyte Contributions to Immune Responses in People With Cystic Fibrosis.

Hisert KB, Birkland TP, Schoenfelt KQ, Long ME, Grogan B, Carter S, Liles WC, McKone EF, Becker L, Manicone AM, Gharib SA.


Front Pharmacol. 2020 Aug 13;11:1219. doi: 10.3389/fphar.2020.01219. eCollection 2020.


PMID: 33013356

Cell type- and replication stage-specific influenza virus responses in vivo.


Fay EJ, Aron SL, Macchietto MG, Markman MW, Esser-Nobis K, Gale M Jr, Shen S, Langlois RA.


PLoS Pathog. 2020 Aug 13;16(8):e1008760. doi: 10.1371/journal.ppat.1008760. Online ahead of print.


PMID: 32790753

A Geroscience Approach to Preventing Pathologic Consequences of COVID-19.

Dou Y, Fatemi S, Darvas M, Gale M Jr, Ladiges W.


J Interferon Cytokine Res. 2020 Aug 13. doi: 10.1089/jir.2020.29018.dou. Online ahead of print.


PMID: 32790488

Direct quantification of single red blood cell hemoglobin concentration with multiphoton microscopy.


Francis AT, Shears MJMurphy SC, Fu D.


Anal Chem. 2020 Aug 12. doi: 10.1021/acs.analchem.0c01609. Online ahead of print.


PMID: 32786430

Proteome-Wide Zika Virus CD4 T Cell Epitope and HLA Restriction Determination.


Campbell VL, Nguyen L, Snoey E, McClurkan CLLaing KJ, Dong L, Sette A, Lindestam Arlehamn CS, Altmann DM, Boyton RJ, Roby JA, Gale M Jr, Stone M, Busch MP, Norris PJ, Koelle DM.


Immunohorizons. 2020 Aug 4;4(8):444-453. doi: 10.4049/immunohorizons.2000068.


PMID: 32753403

Evaluation of highly sensitive diagnostic tools for the detection of P. falciparum in pregnant women attending antenatal care visits in Colombia.


Vásquez AM, Vélez G, Medina A, Serra-Casas E, Campillo A, Gonzalez IJ, Murphy SCSeilie AM, Ding XC, Tobón Castaño A.


BMC Pregnancy Childbirth. 2020 Jul 31;20(1):440. doi: 10.1186/s12884-020-03114-4.


PMID: 32736543

Reexamining the categorical exclusion of pediatric participants from controlled human infection trials.


Murphy SC, Duenas DM, Richie TL, Shah SK.


Bioethics. 2020 Jul 26. doi: 10.1111/bioe.12788. Online ahead of print.


PMID: 32715497

Conducting clinical trials in sub-Saharan Africa: challenges and lessons learned from the Malawi Cryptosporidium study.


Toto N, Douglas E, Gmeiner M, Barrett LK, Lindblad R, Makhaza L, Nedi W, Phulusa J, Quinnan GV, Sawyer LA, Thole H, Van Voorhis WC, Iroh Tam PY.


Trials. 2020 Jul 25;21(1):680. doi: 10.1186/s13063-020-04620-8.


PMID: 32711568

Comparative assessment of the effects of bumped kinase inhibitors on early zebrafish embryo development and pregnancy in mice.

Anghel N, Winzer PA, Imhof D, Müller J, Langa J, Rieder J, Barrett LK, Vidadala RSR, Huang W, Choi RHulverson MAWhitman GRArnold SLVan Voorhis WC, Ojo KK, Maly DJ, Fan E, Hemphill A.


Int J Antimicrob Agents. 2020 Jul 21:106099. doi: 10.1016/j.ijantimicag.2020.106099. Online ahead of print.


PMID: 32707170

An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates.

Erasmus JH, Khandhar AP, O'Connor MA, Walls AC, Hemann EA, Murapa P, Archer J, Leventhal S, Fuller JT, Lewis TB, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M Jr, Veesler D, Berglund P, Heydenburg Fuller D.


Sci Transl Med. 2020 Jul 20:eabc9396. doi: 10.1126/scitranslmed.abc9396. Online ahead of print.


PMID: 32690628

A Humanized Mouse Model for Plasmodium vivax to Test Interventions that Block Liver Stage to Blood Stage Transition and Blood Stage Infection.

Schäfer C, Roobsoong W, Kangwanrangsan N, Bardelli M, Rawlinson TA, Dambrauskas N, Trakhimets O, Parthiban C, Goswami D, Reynolds LM, Kennedy SY, Flannery EL, Murphy SC, Sather DN, Draper SJ, Sattabongkot J, Mikolajczak SA, Kappe SHI.


iScience. 2020 Jul 18;23(8):101381. doi: 10.1016/j.isci.2020.101381. Online ahead of print.


PMID: 32739836


Genetic variation implicates plasma angiopoietin-2 in the development of acute kidney injury sub-phenotypes.


Bhatraju PK, Cohen M, Nagao RJ, Morrell ED, Kosamo S, Chai XY, Nance R, Dmyterko V, Delaney J, Christie JD, Liu KD, Mikacenic C, Gharib SA, Liles WC, Zheng Y, Christiani DC, Himmelfarb J, Wurfel MM.


BMC Nephrol. 2020 Jul 17;21(1):284. doi: 10.1186/s12882-020-01935-1.


PMID: 32680471 [PubMed - as supplied by publisher]

Donor-derived CD4+ T cells and HHV-6B reactivation after allogeneic hematopoietic cell transplantation.

Hanson DJ, Xie H, Zerr DM, Leisenring WM, Jerome KR, Huang ML, Stevens-Ayers T, Boeckh M, Koelle DM, Hill JA.


J Infect Dis. 2020 Jul 14. pii: jiaa422. doi: 10.1093/infdis/jiaa422. [Epub ahead of print]


PMID: 32663845 [PubMed - as supplied by publisher]

Unnecessary hesitancy on human vaccine tests-Response.


Shah SK, Miller FG, Darton TC, Duenas D, Emerson C, Lynch HF, Jamrozik E, Jecker NS, Kamuya D, Kapulu M, Kimmelman J, MacKay D, Memoli MJ, Murphy SC, Palacios R, Richie TL, Roestenberg M, Saxena A, Saylor K, Selgelid MJ, Vaswani V, Rid A.


Science. 2020 Jul 10;369(6500):151. doi: 10.1126/science.abc9380. No abstract available.


PMID: 32646992 [PubMed - in process]

Safety, pharmacokinetics and causal prophylactic efficacy of KAF156 in a Plasmodium falciparum human infection study.


Kublin JG, Murphy SC, Maenza J, Seilie AM, Jain JP, Berger D, Spera D, Zhao R, Soon RL, Czartoski JL, Potochnic MA, Duke E, Chang M, Vaughan A, Kappe SHI, Leong FJ, Pertel P, Prince WT.


Clin Infect Dis. 2020 Jul 9. pii: ciaa952. doi: 10.1093/cid/ciaa952. [Epub ahead of print]


PMID: 32644127 [PubMed - as supplied by publisher]

sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country.

Wright SW, Lovelace-Macon L, Hantrakun V, Rudd KE, Teparrukkul P, Kosamo S, Liles WC, Limmathurotsakul D, West TE.


BMC Med. 2020 Jul 1;18(1):159. doi: 10.1186/s12916-020-01627-5.


PMID: 32605575 [PubMed - in process]

Predicting Vibrio cholerae infection and disease severity using metagenomics in a prospective cohort study.


Levade I, Saber MM, Midani F, Chowdhury F, Khan AI, Begum YA, Ryan ET, David LA, Calderwood SB, Harris JB, LaRocque RC, Qadri F, Shapiro BJ, Weil AA.


J Infect Dis. 2020 Jul 1. pii: jiaa358. doi: 10.1093/infdis/jiaa358. [Epub ahead of print]


PMID: 32610345 [PubMed - as supplied by publisher]

Optimal priming of poxvirus vector (NYVAC)-based HIV vaccine regimens for T cell responses requires three DNA injections. Results of the randomized multicentre EV03/ANRS VAC20 Phase I/II Trial.

Lévy Y, Lacabaratz C, Ellefsen-Lavoie K, Stöhr W, Lelièvre JD, Bart PA, Launay O, Weber J, Salzberger B, Wiedemann A, Surenaud M, Koelle DM, Wolf H, Wagner R, Rieux V, Montefiori DC, Yates NL, Tomaras GD, Gottardo R, Mayer B, Ding S, Thiébaut R, McCormack S, Chêne G, Pantaleo G.


PLoS Pathog. 2020 Jun 26;16(6):e1008522. doi: 10.1371/journal.ppat.1008522. eCollection 2020 Jun.


PMID: 32589686 [PubMed - as supplied by publisher]

Spatiotemporal dynamics of innate immune signaling via RIG-I-like receptors.


Esser-Nobis K, Hatfield LD, Gale M Jr.


Proc Natl Acad Sci U S A. 2020 Jun 22. pii: 201921861. doi: 10.1073/pnas.1921861117. [Epub ahead of print]


PMID: 32571931 [PubMed - as supplied by publisher]

A randomized controlled trial of isoniazid to prevent Mycobacterium tuberculosis infection in Kenyan HIV-exposed uninfected infants.

LaCourse SM, Richardson BA, Kinuthia J, Warr AJ, Maleche-Obimbo E, Matemo D, Cranmer LM, Mecha J, Escudero JN, Hawn TR, John-Stewart G.


Clin Infect Dis. 2020 Jun 21. pii: ciaa827. doi: 10.1093/cid/ciaa827. [Epub ahead of print]


PMID: 32564076 [PubMed - as supplied by publisher]

Taming the Boys for Global Good: Contraceptive Strategy to Stop Malaria Transmission.


Choi RMichaels SA, Onu EC, Hulverson MA, Saha A, Coker ME, Weeks JC, Van Voorhis WCOjo KK.


Molecules. 2020 Jun 16;25(12). pii: E2773. doi: 10.3390/molecules25122773. Review.


PMID: 32560085 [PubMed - as supplied by publisher]

Neospora caninum: Differential Proteome of Multinucleated Complexes Induced by the Bumped Kinase Inhibitor BKI-1294.


Winzer P, Müller J, Imhof D, Ritler D, Uldry AC, Braga-Lagache S, Heller M, Ojo KKVan Voorhis WC, Ortega-Mora LM, Hemphill A.


Microorganisms. 2020 May 26;8(6). pii: E801. doi: 10.3390/microorganisms8060801.


PMID: 32466554 [PubMed]

In silico detection of SARS-CoV-2 specific B-cell epitopes and validation in ELISA for serological diagnosis of COVID-19. 

Phan IQ, Subramanian S, Kim D, Carter L, King N, Anishchenko I, Barrett LKCraig JTillery TShek R, Harrington WE, Koelle DM, Wald A, Boonyaratanakornkit J, Isoherranen N, Greninger AL, Jerome KR, Chu H, Staker B, Stewart L, Myler PJ, Van Voorhis WC

2020 May 25. doi: 10.1101/2020.05.22.111526.

Neospora caninum: Structure and Fate of Multinucleated Complexes Induced by the Bumped Kinase Inhibitor BKI-1294.


Winzer P, Anghel N, Imhof D, Balmer V, Ortega-Mora LM, Ojo KKVan Voorhis WC, Müller J, Hemphill A.


Pathogens. 2020 May 16;9(5). pii: E382. doi: 10.3390/pathogens9050382.


PMID: 32429314 [PubMed]

B cell intrinsic expression of IFNλ receptor suppresses the acute humoral immune response to experimental blood-stage malaria.


Hahn WO, Pepper M, Liles WC.


Virulence. 2020 May 14. doi: 10.1080/21505594.2020.1768329. [Epub ahead of print]


PMID: 32407154 [PubMed - as supplied by publisher]

The early local and systemic Type I interferon responses to ultraviolet B light exposure are cGAS dependent.


Skopelja-Gardner S, An J, Tai J, Tanaka L, Sun X, Hermanson P, Baum R, Kawasumi M, Green RGale M Jr, Kalus A, Werth VP, Elkon KB.


Sci Rep. 2020 May 13;10(1):7908. doi: 10.1038/s41598-020-64865-w.


PMID: 32404939 [PubMed - in process]

Ethics of controlled human infection to study COVID-19.


Shah SK, Miller FG, Darton TC, Duenas D, Emerson C, Lynch HF, Jamrozik E, Jecker NS, Kamuya D, Kapulu M, Kimmelman J, MacKay D, Memoli MJ, Murphy SC, Palacios R, Richie TL, Roestenberg M, Saxena A, Saylor K, Selgelid MJ, Vaswani V, Rid A.


Science. 2020 May 7. pii: eabc1076. doi: 10.1126/science.abc1076. [Epub ahead of print]


PMID: 32381590 [PubMed - as supplied by publisher]

Systematic Profiling of Full-Length Ig and TCR Repertoire Diversity in Rhesus Macaque through Long Read Transcriptome Sequencing.


Brochu HN, Tseng E, Smith EThomas MJ, Jones AM, Diveley KR, Law L, Hansen SG, Picker LJ, Gale M Jr, Peng X.


J Immunol. 2020 May 6. pii: ji1901256. doi: 10.4049/jimmunol.1901256. [Epub ahead of print]


PMID: 32376650 [PubMed - as supplied by publisher]

An interferon-gamma release assay as a novel biomarker in systemic lupus erythematosus.


Thomason JL, Obih UM, Koelle DM, Lood C, Hughes AG.


Rheumatology (Oxford). 2020 May 6. pii: keaa161. doi: 10.1093/rheumatology/keaa161. [Epub ahead of print]


PMID: 32375180 [PubMed - as supplied by publisher]

Vancomycin improves Plasmodium yoelii malaria parasite in vitro liver stage cultures by controlling Elizabethkingia anophelis, a bacterium in the microbiome of lab-reared Anopheles mosquitoes.

Shears MJMurphy SC.


Mol Biochem Parasitol. 2020 Apr 30:111279. doi: 10.1016/j.molbiopara.2020.111279. [Epub ahead of print]


PMID: 32360511 [PubMed - as supplied by publisher]

Electronic Consults for Infectious Diseases in a United States Multisite Academic Health System.


Wood BR, Bender JA, Jackson S, Rosengaus L, Pottinger PS, Gottlieb GS, Dhanireddy S, Harrington RD, Pruzhanskaya Y, Chew LD, Scott JD.


Open Forum Infect Dis. 2020 Mar 20;7(4):ofaa101. doi: 10.1093/ofid/ofaa101. eCollection 2020 Apr.


PMID: 32328507 [PubMed]

Innate Immunity in Hepatitis C Virus Infection.


Schwerk J, Negash A, Savan R, Gale M Jr.


Cold Spring Harb Perspect Med. 2020 Apr 27. pii: a036988. doi: 10.1101/cshperspect.a036988. [Epub ahead of print]


PMID: 32341066 [PubMed - as supplied by publisher]

RIG-I-like receptor activation drives type I IFN and antiviral signaling to limit Hantaan orthohantavirus replication.


Kell AM, Hemann EA, Turnbull JBGale M Jr.


PLoS Pathog. 2020 Apr 24;16(4):e1008483. doi: 10.1371/journal.ppat.1008483. [Epub ahead of print]


PMID: 32330200 [PubMed - as supplied by publisher]

Ivacaftor decreases monocyte sensitivity to interferon-γ in people with cystic fibrosis.


Hisert KB, Birkland TP, Schoenfelt KQ, Long ME, Grogan B, Carter S, Liles WC, McKone EF, Becker L, Manicone AM.


ERJ Open Res. 2020 Apr 19;6(2). pii: 00318-2019. doi: 10.1183/23120541.00318-2019. eCollection 2020 Apr.


PMID: 32337217 [PubMed - a supplied by published]

Clofazimine for treatment of cryptosporidiosis in HIV-infected adults (CRYPTOFAZ): an experimental medicine, randomized, double-blind, placebo-controlled phase 2a trial.


Iroh Tam PY, Arnold SLMBarrett LK, Chen CR, Conrad TM, Douglas E, Gordon MA, Hebert D, Henrion M, Hermann D, Hollingsworth B, Houpt E, Jere KC, Lindblad R, Love MS, Makhaza L, McNamara CW, Nedi W, Nyirenda J, Operario DJ, Phulusa J, Quinnan GV, Sawyer LA, Thole H, Toto N, Winter A, Van Voorhis WC.


Clin Infect Dis. 2020 Apr 11. pii: ciaa421. doi: 10.1093/cid/ciaa421. [Epub ahead of print]


PMID: 32277809 [PubMed - as supplied by publisher]

Hydroxychloroquine for treatment of SARS-CoV-2 infection? Improving our confidence in a model-based approach to dose selection.


Arnold SLBuckner F.


Clin Transl Sci. 2020 Apr 8. doi: 10.1111/cts.12797. [Epub ahead of print]


PMID: 32268005 [PubMed - as supplied by publisher]


Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling.


Roby JA, Esser-Nobis K, Dewey-Verstelle EC, Fairgrieve MR, Schwerk J, Lu AY, Soveg FW, Hemann EA, Hatfield LD, Keller BC, Shapiro A, Forero A, Stencel-Baerenwald JE, Savan R, Gale M Jr.


Cells. 2020 Apr 7;9(4). pii: E899. doi: 10.3390/cells9040899.

PMID: 32272626 [PubMed - in process]



WHO malaria nucleic acid amplification test external quality assessment scheme: results of distribution programmes one to three.


Cunningham JA, Thomson RM, Murphy SC, de la Paz Ade M, Ding XC, Incardona S, Legrand E, Lucchi NW, Menard D, Nsobya SL, Saez AC, Chiodini PL, Shrivastava J.


Malar J. 2020 Mar 30;19(1):129. doi: 10.1186/s12936-020-03200-0.


PMID: 32228615 [PubMed - in process]

Long-term experience and outcomes of programmatic antiretroviral therapy for HIV-2 infection in Senegal, West Africa.


Raugi DN, Ba S, Cisse O, Diallo K, Tamba IT, Ndour C, Badiane NMD, Fortes L, Diallo MBFaye DSmith RASall F, Toure MSall EI, Diallo Agne H, Faye KDiatta JP, Sy MP, Chang M, Diaw B, Sambou J, Bakhoum R, Sy MD, Niang A, Malomar JJCoombs RWHawes SE, Ndoye I, Kiviat NBSow PSSeydi MGottlieb GS; University of Washington-Senegal HIV-2 Study Group.


Clin Infect Dis. 2020 Mar 30. pii: ciaa277. doi: 10.1093/cid/ciaa277. [Epub ahead of print]


PMID: 32227115 [PubMed - as supplied by publisher]

Polyomavirus-driven Merkel cell carcinoma: Prospects for therapeutic vaccine development.


Tabachnick-Cherny S, Pulliam T, Church C, Koelle DM, Nghiem P.


Mol Carcinog. 2020 Mar 27. doi: 10.1002/mc.23190. [Epub ahead of print]


PMID: 32219902 [PubMed - as supplied by publisher]

Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned.


Choi RHulverson MA, Huang W, Vidadala RSR, Whitman GRBarrett LK, Schaefer DA, Betzer DP, Riggs MW, Stone Doggett J, Hemphill A, Miguel Ortega-Mora L, McCloskey MCArnold SLM, Hackman RC, Marsh KC, Lynch JJ, Freiberg GM, Leroy BE, Kempf DJ, Choy RKM, de Hostos EL, Maly DJ, Fan E, Ojo KKVan Voorhis WC.


Int J Parasitol. 2020 Mar 26. pii: S0020-7519(20)30056-4. doi: 10.1016/j.ijpara.2020.01.006. [Epub ahead of print] Review.


PMID: 32224121 [PubMed - as supplied by publisher]

Trends in Reported Sexual Behavior and Y-chromosomal DNA Detection among Female Secx Workers in the Senegal PrEP Demonstration Project. 


Roberts DA, Hawes SE, Bousso Bao MD, Ndiaye AJ, Gueye D, Raugi DN, Mane M, Mboup A, Diouf O, Jones F, Kane CT, Sarr M, Mboup S, Gottlieb GS; Senegal PrEP Demonstration Project Team. 


Sex Transm Dis. 2020 Mar 16. doi: 10.1097/OLQ.0000000000001175. [Epub ahead of print]


PMID: 32187172 [PubMed - as supplied by publisher]

Wikidata as knowledge graph for the life sciences.

Waagmeester A, Stupp G, Burgstaller-Muehlbacher S, Good BM, Griffith M, Griffith OL, Hanspers K, Hermjakob H, Hudson TS, Hybiske K, Keating SM, Manske M, Mayers M, Mietchen D, Mitraka E, Pico AR, Putman T, Riutta A, Queralt-Rosinach N, Schriml LM, Shafee T, Slenter D, Stephan R, Thornton K, Tsueng G, Tu R, Ul-Hasan S, Willighagen E, Wu C, Su AI.



2020 Mar 17;9. pii: e52614. doi: 10.7554/eLife.52614.


PMID: 32180547 [PubMed - in process]

Prevalent and diverse intratumoral oncoprotein-specific CD8+ T cells within polyoma virus-driven Merkel cell carcinomas.


Jing L, Ott M, Church CD, Kulikauskas RM, Ibrani D, Iyer JG, Afanasiev OK, Colunga A, Cook MM, Xie H, Greninger AL, Paulson KG, Chapuis AG, Bhatia S, Nghiem P, Koelle DM.


Cancer Immunol Res. 2020 Mar 16. pii: canimm.0647.2019. doi: 10.1158/2326-6066.CIR-19-0647. [Epub ahead of print]


PMID: 32179557 [PubMed - as supplied by publisher]

Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition.


Gorini G, Fourati S, Vaccari M, Rahman MA, Gordon SN, Brown DR, Law L, Chang J, Green R, Barrenäs F, Liyanage NPM, Doster MN, Schifanella L, Bissa M, Silva de Castro I, Washington-Parks R, Galli V, Fuller DH, Santra S, Agy M, Pal R, Palermo RE, Tomaras GD, Shen X, LaBranche CC, Montefiori DC, Venzon DJ, Trinh HV, Rao M, Gale M Jr, Sekaly RP, Franchini G.


PLoS Pathog. 2020 Mar 12;16(3):e1008377. doi: 10.1371/journal.ppat.1008377. [Epub ahead of print]


PMID: 32163525 [PubMed - as supplied by publisher]


African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity.


Raehtz KD, Barrenäs F, Xu C, Busman-Sahay K, Valentine A, Law L, Ma D, Policicchio BB, Wijewardana V, Brocca-Cofano E, Trichel A, Gale M Jr, Keele BF, Estes JD, Apetrei C, Pandrea I.


PLoS Pathog. 2020 Mar 2;16(3):e1008333. doi: 10.1371/journal.ppat.1008333. [Epub ahead of print]


PMID: 32119719 [PubMed - as supplied by publisher]


SJS/TEN 2019: From science to translation.

Chang WC, Abe R, Anderson P, Anderson W, Ardern-Jones MR, Beachkofsky TM, Bellón T, Biala AK, Bouchard C, Cavalleri GL, Chapman N, Chodosh J, Choi HK, Cibotti RR, Divito SJ, Dewar K, Dehaeck U, Etminan M, Forbes D, Fuchs E, Goldman JL, Holmes JH 4th, Hope EA, Hung SI, Hsieh CL, Iovieno A, Jagdeo J, Kim MK, Koelle DM, Lacouture ME, Le Pallec S, Lehloenya RJ, Lim R, Lowe A, McCawley J, McCawley J, Micheletti RG, Mockenhaupt M, Niemeyer K, Norcross MA, Oboh D, Olteanu C, Pasieka HB, Peter J, Pirmohamed M, Rieder M, Saeed HN, Shear NH, Shieh C, Straus S, Sukasem C, Sung C, Trubiano JA, Tsou SY, Ueta M, Volpi S, Wan C, Wang H, Wang ZQ, Weintraub J, Whale C, Wheatley LM, Whyte-Croasdaile S, Williams KB, Wright G, Yeung SN, Zhou L, Chung WH, Phillips EJ, Carleton BC.


J Dermatol Sci. 2020 Mar 7. pii: S0923-1811(20)30064-5. doi: 10.1016/j.jdermsci.2020.02.003. [Epub ahead of print] Review.


PMID: 32192826 [PubMed - as supplied by publisher]


Mechanisms of endogenous HIV-1 reactivation by endocervical epithelial cells.


Gornalusse GG, Valdez R, Fenkart G, Vojtech L, Fleming L, Pandey U, Hughes S, Levy C, Dela Cruz EJ, Calienes F, Kirby AC, Fialkow MF, Lentz GM, Wagoner J, Jing L, Koelle DM, Polyak SJ, Fredricks DN, McElrath MJ, Wald A, Hladik F.


J Virol. 2020 Feb 12. pii: JVI.01904-19. doi: 10.1128/JVI.01904-19. [Epub ahead of print]


PMID: 32051273 [PubMed - as supplied by publisher]

T Cell Responses to Mycobacterial Glycolipids: On the Spectrum of "Innateness".


James CASeshadri C.


Front Immunol. 2020 Feb 11;11:170. doi: 10.3389/fimmu.2020.00170. eCollection 2020. Review.


PMID: 32117300 [PubMed - in process]

Phenotypic Drug Discovery for Human African Trypanosomiasis: A Powerful Approach.


Buckner FS, Buchynskyy A, Nagendar P, Patrick DA, Gillespie JR, Herbst Z, Tidwell RR, Gelb MH.


Trop Med Infect Dis. 2020 Feb 5;5(1). pii: E23. doi: 10.3390/tropicalmed5010023.

PMID: 32033395 [PubMed] 

Methionyl-tRNA synthetase inhibitor has potent in vivo activity in a novel Giardia lamblia luciferase murine infection model.


Michaels SA, Shih HW, Zhang B, Navaluna ED, Zhang Z, Ranade RMGillespie JR, Merritt EA, Fan E, Buckner FS, Paredez AR, Ojo KK.


J Antimicrob Chemother. 2020 Feb 3. pii: dkz567. doi: 10.1093/jac/dkz567. [Epub ahead of print]


PMID: 32011682 [PubMed - as supplied by publisher]

Clinical Development of New TB Vaccines: Recent Advances and Next Steps.


Hatherill M, White RG, Hawn TR.


Front Microbiol. 2020 Jan 30;10:3154. doi: 10.3389/fmicb.2019.03154. eCollection 2019. Review.


PMID: 32082273 [PubMed]

Human DNA-PK activates a STING-independent DNA sensing pathway.


Burleigh K, Maltbaek JH, Cambier S, Green RGale M Jr, James RC, Stetson DB.


Sci Immunol. 2020 Jan 24;5(43). pii: eaba4219. doi: 10.1126/sciimmunol.aba4219.


PMID: 31980485 [PubMed - in process]

Infant TB Infection Prevention Study (iTIPS): a randomised trial protocol evaluating isoniazid to prevent M. tuberculosis infection in HIV-exposed uninfected children.


LaCourse SM, Richardson BA, Kinuthia J, Warr AJ, Maleche-Obimbo E, Matemo D, Cranmer LM, Escudero JN, Hawn TR, John-Stewart GC.


BMJ Open. 2020 Jan 21;10(1):e034308. doi: 10.1136/bmjopen-2019-034308.


PMID: 31969368 [PubMed - in process]

Expanded Spectrum of Antiretroviral-Selected Mutations in Human Immunodeficiency Virus Type 2


Tzou PL, Descamps D, Rhee SY, Raugi DN, Charpentier C, Taveira N, Smith RA, Soriano V, de Mendoza C, Holmes SP, Gottlieb GS, Shafer RW.


J Infect Dis. 2020 Jan 22. pii: jiaa026. doi: 10.1093/infdis/jiaa026. [Epub ahead of print]


PMID: 31965175 [PubMed - as supplied by publisher]

Towards a structome of Acinetobacter baumannii drug targets.


Tillery LBarrett K, Dranow DM, Craig J, Shek R, Chun I, Barrett LK, Phan I, Subramanian S, Abendroth J, Lorimer DD, Edwards TE, Van Voorhis WC.


Protein Sci. 2020 Jan 12. doi: 10.1002/pro.3826. [Epub ahead of print]


PMID: 31930600 [PubMed - as supplied by publisher]

Structures of glyceraldehyde 3-phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis.


Barrett KF, Dranow DM, Phan IQ, Michaels SA, Shaheen S, Navaluna ED, Craig JKTillery LM, Choi R, Edwards TE, Conrady DG, Abendroth J, Horanyi PS, Lorimer DD, Van Voorhis WC, Zhang Z, Barrett LK, Subramanian S, Staker B, Fan E, Myler P, Soge OO, Hybiske KOjo KK.


Protein Sci. 2020 Jan 12. doi: 10.1002/pro.3824. [Epub ahead of print]


PMID: 31930578 [PubMed - as supplied by publisher]

Solution structure for an Encephalitozoon cuniculi adrenodoxin-like protein in the oxidized state.

Shaheen S, Barrett KF, Subramanian S, Arnold SLM, Laureanti JA, Myler PJ, Van Voorhis WC, Buchko GW.


Protein Sci. 2020 Jan 8. doi: 10.1002/pro.3818. [Epub ahead of print]


PMID: 31912584 [PubMed - as supplied by publisher]

Endothelial activation, innate immune activation, and inflammation are associated with post-bronchodilator airflow limitation and obstruction among adolescents living with HIV.


Attia EF, Bhatraju PK, Triplette M, Kosamo S, Maleche-Obimbo E, West TE, Richardson B, Zifodya JS, Eskander S, Njiru CD, Warui D, Kicska GA, Chung MH, Crothers K, Liles WC, Graham SM.


J Acquir Immune Defic Syndr. 2020 Jan 7. doi: 10.1097/QAI.0000000000002255. [Epub ahead of print]


PMID: 31917749 [PubMed - as supplied by publisher]

A 71-year-old man with recurrent pulmonary mycobacterial avium complex infections and lymphopenia.


Al-Shaikhly T, Buckner FS, Altman MC, Ochs HD, Ayars AG.


Allergy Asthma Proc. 2020 Jan 1;41(1):66-69. doi: 10.2500/aap.2020.41.190003.


PMID: 31888785 [PubMed - in process]

ACS Infectious Diseases: Special Issue Focused on Gut Pathogens.

Van Voorhis WC, Calderón F.


ACS Infect Dis. 2019 Dec 23. doi: 10.1021/acsinfecdis.9b00432. [Epub ahead of print] No abstract available.


PMID: 31868345 [PubMed - as supplied by publisher]

Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: A randomized double blinded phase I/IIa trial.

Chandra J, Woo WP, Dutton JL, Xu Y, Li B, Kinrade S, Druce J, Finlayson N, Griffin P, Laing KJKoelle DM, Frazer IH.


PLoS One. 2019 Dec 17;14(12):e0226320. doi: 10.1371/journal.pone.0226320. eCollection 2019.


PMID: 31846475 [PubMed - in process]

Large benefits to youth-focused HIV treatment-as-prevention efforts in generalized heterosexual populations: An agent-based simulation model.

Mittler JE, Murphy JT, Stansfield SE, Peebles KC, Gottlieb GS, Abernethy NF, Reid MC, Goodreau SM, Herbeck JT.


PLoS Comput Biol. 2019 Dec 17;15(12):e1007561. doi: 10.1371/journal.pcbi.1007561. [Epub ahead of print]


PMID: 31846456 [PubMed - as supplied by publisher]

Polymorphisms in Interferon Pathway Genes and Risk of Mycobacterium tuberculosis Infection in Contacts of Tuberculosis Cases in Brazil.

Cubillos-Angulo JM, Arriaga MB, Melo MGM, Silva EC, Alvarado-Arnez LE, de Almeida AS, Moraes MO, Moreira ASR, Lapa E Silva JR, Fukutani KF, Sterling TR, Hawn TR, Kritski AL, Oliveira MM, Andrade BB.


Int J Infect Dis. 2019 Dec 13. pii: S1201-9712(19)30486-2. doi: 10.1016/j.ijid.2019.12.013. [Epub ahead of print]


PMID: 31843671 [PubMed - as supplied by publisher]


Author Correction: Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control.


Barrenas F, Raehtz K, Xu C, Law LGreen RR, Silvestri G, Bosinger SE, Nishida A, Li Q, Lu W, Zhang J, Thomas MJ, Chang JSmith E, Weiss JM, Dawoud RA, Richter GH, Trichel A, Ma D, Peng X, Komorowski J, Apetrei C, Pandrea I, Gale M Jr.


Nat Commun. 2019 Dec 13;10(1):5768. doi: 10.1038/s41467-019-13816-9.


PMID: 31836755 [PubMed - in process]

Setting Our Sights on Infectious Diseases.


De Rycker M, Horn D, Aldridge B, Amewu RK, Barry CE 3rd, Buckner FS, Cook S, Ferguson MAJ, Gobeau N, Herrmann J, Herrling P, Hope W, Keiser J, Lafuente-Monasterio MJ, Leeson PD, Leroy D, Manjunatha UH, McCarthy J, Miles TJ, Mizrahi V, Moshynets O, Niles J, Overington JP, Pottage J, Rao SPS, Read KD, Ribeiro I, Silver LL, Southern J, Spangenberg T, Sundar S, Taylor C, Van Voorhis W, White NJ, Wyllie S, Wyatt PG, Gilbert IH.


ACS Infect Dis. 2019 Dec 6. doi: 10.1021/acsinfecdis.9b00371. [Epub ahead of print]


PMID: 31808676 [PubMed - as supplied by publisher]

MEK1 regulates pulmonary macrophage inflammatory responses and resolution of acute lung injury.


Long ME, Gong KQ, Eddy WE, Volk JS, Morrell ED, Mikacenic C, West TE, Skerrett SJ, Charron J, Liles WC, Manicone AM.


JCI Insight. 2019 Dec 5;4(23). pii: 132377. doi: 10.1172/jci.insight.132377.


PMID: 31801908 [PubMed - in process]

Vibrio cholerae at the Intersection of Immunity and the Microbiome.


Weil AA, Becker RL, Harris JB.


mSphere. 2019 Nov 27;4(6). pii: e00597-19. doi: 10.1128/mSphere.00597-19. Review.


PMID: 31776240 [PubMed - in process]

Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.


Chamcha V, Reddy PBJ, Kannanganat S, Wilkins C, Gangadhara S, Velu V, Green RLaw GLChang J, Bowen JR, Kozlowski PA, Lifton M, Santra S, Legere T, Chea LS, Chennareddi L, Yu T, Suthar MS, Silvestri G, Derdeyn CA, Gale M Jr, Villinger F, Hunter E, Amara RR.


Sci Transl Med. 2019 Nov 20;11(519). pii: eaav1800. doi: 10.1126/scitranslmed.aav1800.


PMID: 31748228 [PubMed - in process]

Immune responses to O-specific polysaccharide (OSP) in North American adults infected with Vibrio cholerae O1 Inaba.


Hossain M, Islam K, Kelly M, Mayo Smith LM, Charles RC, Weil AA, Bhuiyan TR, Kováč P, Xu P, Calderwood SB, Simon JK, Chen WH, Lock M, Lyon CE, Kirkpatrick BD, Cohen M, Levine MM, Gurwith M, Leung DT, Azman AS, Harris JB, Qadri F, Ryan ET.


PLoS Negl Trop Dis. 2019 Nov 19;13(11):e0007874. doi: 10.1371/journal.pntd.0007874. eCollection 2019 Nov.


PMID: 31743334 [PubMed - in process]

RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions.


Schwerk J, Soveg FW, Ryan AP, Thomas KR, Hatfield LD, Ozarkar S, Forero A, Kell AM, Roby JA, So L, Hyde JL, Gale M Jr, Daugherty MD, Savan R.


Nat Immunol. 2019 Nov 18. doi: 10.1038/s41590-019-0527-6. [Epub ahead of print]


PMID: 31740798 [PubMed - as supplied by publisher]

Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control.

Barrenas F, Raehtz K, Xu C, Law LGreen RR, Silvestri G, Bosinger SE, Nishida A, Li Q, Lu W, Zhang J, Thomas MJ, Chang JSmith E, Weiss JM, Dawoud RA, Richter GH, Trichel A, Ma D, Peng X, Komorowski J, Apetrei C, Pandrea I, Gale M Jr.


Nat Commun. 2019 Nov 8;10(1):5101. doi: 10.1038/s41467-019-12987-9.


PMID: 31704931 [PubMed - in process]

Trillions and Trillions: Herpes Simplex Virus-1 Hepatitis in an Immunocompetent Adult.


Ikuta K, Roychoudhury P, Xie H, McClurken CL, Walkiewicz M, Makhsous N, Huang ML, Beru Y, Alam M, Shepherd A, Lamotte ED, Patel K, Morris A, Ҫoruh B, Yu L, Bhattacharya R, Cheng R, Walter RB, Limaye AP, Lockwood CM, Holland SM, Rakita RM, Koelle DM, Greninger AL.


Open Forum Infect Dis. 2019 Nov 5;6(11):ofz465. doi: 10.1093/ofid/ofz465. eCollection 2019 Nov.


PMID: 31777756 [PubMed]

A new chemotype with promise against Trypanosoma cruzi.

Wang X, Cal M, Kaiser M, Buckner FS, Lepesheva GI, Sanford AG, Wallick AI, Davis PH, Vennerstrom JL.


Bioorg Med Chem Lett. 2019 Oct 31:126778. doi: 10.1016/j.bmcl.2019.126778. [Epub ahead of print]


PMID: 31706668 [PubMed - as supplied by publisher]

Back Pain in a 23-Year-Old Male With X-Linked Chronic Granulomatous Disease.

Sabo MC, Blain M, McCulloch D, Glasgow HL, Sengupta DJ, Le T, Cookson BT, Pottinger PS, Liles WC, Graham SM.


Open Forum Infect Dis. 2019 Oct 18;6(11):ofz449. doi: 10.1093/ofid/ofz449. eCollection 2019 Nov.


PMID: 31723573 [PubMed]

Immune Evasion Strategies Used by Zika Virus to Infect the Fetal Eye and Brain.

Nelson BR, Roby JA, Dobyns WB, Rajagopal L, Gale M Jr, Adams Waldorf KM.


Viral Immunol. 2019 Nov 5. doi: 10.1089/vim.2019.0082. [Epub ahead of print]


PMID: 31687902 [PubMed - as supplied by publisher]

Growth Rate of Plasmodium falciparum: Analysis of Parasite Growth Data from Malaria Volunteer Infection Studies.


Wockner LF, Hoffmann I, Webb L, Mordmüller B, Murphy SC, Kublin JG, O'Rourke P, McCarthy JS, Marquart L.


J Infect Dis. 2019 Nov 4. pii: jiz557. doi: 10.1093/infdis/jiz557. [Epub ahead of print]


PMID: 31679015 [PubMed - as supplied by publisher]

October Publication Round-Up!

Scroll through the 5 CERID publications from CERID labs, PIs, and lab technicians publications that have hit the PubMed stands since the end of September! The scope of the individual publications is wide, covering a number of important bacteria and parasites from Mycobacterium tuberculosis to Plasmodium falciparum. Read on for highlights from the abstract and the diseases studied in this month’s publication round-up by following the links!

Click here!

Nicotinamide limits replication of Mycobacterium tuberculosis and BCG within macrophages.


Simmons JDPeterson GJCampo M, Lohmiller J, Skerrett SJ, Tunaru S, Offermanns S, Sherman DR, Hawn TR.


J Infect Dis. 2019 Oct 31. pii: jiz541. doi: 10.1093/infdis/jiz541. [Epub ahead of print]


PMID: 31665359 [PubMed - as supplied by publisher]


Importance of study design and phenotype definition in ongoing studies of resistance to latent M. tuberculosis infection.


Stein CM, Mayanja-Kizza H, Hawn TR, Boom WH.


J Infect Dis. 2019 Oct 30. pii: jiz539. doi: 10.1093/infdis/jiz539. [Epub ahead of print] No abstract available.


PMID: 31665355 [PubMed - as supplied by publisher]

Chemoprophylaxis vaccination: Phase 1 study to explore stage-specific immunity to Plasmodium falciparum in U.S. adults. 

Healy SA, Murphy SC, Hume JCC, Shelton L, Kuntz S, Van Voorhis WC, Moodie Z, Metch B, Wang R, Silver-Brace T, Fishbaugher M, Kennedy M, Finney OC, Chaturvedi R, Hobbs CV, Warner-Lubin M, Talley AK, Wong-Madden S, Stuart K, Wald A, Kappe SH, Kublin JG, Duffy PE.


Clin Infect Dis. 2019 Oct 17. pii: ciz1010. doi: 10.1093/cid/ciz1010. [Epub ahead of print]


PMID: 31621832 [PubMed - as supplied by publisher]

The Murine Intravaginal HSV-2 Challenge Model for Investigation of DNA Vaccines. 

Marshak JO, Dong L, Koelle DM

Methods Mol Biol. 2020;2060:529-454. doi: 10.1007/978-1-4939-9814-2_27.

PMID: 31617196 [PubMed - in process]

Single cell transcriptomics reveal polyclonal memory T cell responses in abacavir patch test positive skin. 

Redwood AJ, Rwandamuriye F, Chopra A, Leary S, Ram R, McDonnell W, Konvinse K, White K, Pavlos R, Koelle DM, Mallal S, Phillips E.


J Allergy Clin Immunol. 2019 Sep 28. pii: S0091-6749(19)31249-7. doi: 10.1016/j.jaci.2019.09.013. [Epub ahead of print]


PMID: 31574267 [PubMed - as supplied by publisher]

September Publication Round-Up!

Scroll through the 5 CERID publications from CERID labs, PIs, and lab technicians publications that have hit the PubMed stands since the end of August! The scope of the individual publications is wide, covering a number of important pathogens and viruses from Shigella flexneri to neuropathological West Nile virus infections. Read on for highlights from the abstract and the diseases studied in this month’s publication round up by following the links!

Read here!

Parotid Gland Tumours: Our Experience.

Chauhan N, Shah JA. 

Indian J Otolaryngol Head Neck Surg. 2019 Sep;71(3):378-382. doi: 10.1007/s12070-018-1413-5. Epub 2018 May 31

PMID: 31559207 [PubMed]


Evaluation of in vitro and in vivo antibiotic efficacy against a novel bioluminescent Shigella flexneri.

McCloskey MC, Shaheen S, Rabago L, Hulverson MA, Choi R, Barrett LK, Arnold SLM.


Sci Rep. 2019 Sep 19;9(1):13567. doi: 10.1038/s41598-019-49729-2.


PMID: 31537849 [PubMed - in process]

Introduction to the Special Issue.

Gale M Jr, Savan R.


J Interferon Cytokine Res. 2019 Sep 13. doi: 10.1089/jir.2019.29016.mgj. [Epub ahead of print] No abstract available.


PMID: 31517557 [PubMed - as supplied by publisher]

Chromosomal recombination targets in Chlamydia interspecies lateral gene transfer.


Suchland RJ, Carrell SJ, Wang YHybiske K, Kim DB, Dimond ZE, Hefty PS, Rockey DD.


J Bacteriol. 2019 Sep 9. pii: JB.00365-19. doi: 10.1128/JB.00365-19. [Epub ahead of print]


PMID: 31501285 [PubMed - as supplied by publisher]

Development of transposon mutagenesis for Chlamydia muridarum

Wang Y, LaBrie SD, Carrell SJ, Suchland RJ, Dimond ZE, Kwong F, Rockey DD, Hefty PS, Hybiske K.

J Bacteriol. 2019 Sep 9. pii: JB.00366-19. doi: 10.1128/JB.00366-19. [Epub ahead of print]

PMID: 31501283 [PubMed - as supplied by publisher]

Microglia in Memory Decline from Zika Virus and West Nile Virus Infection. 

Tisoncik-Go J, Gale M Jr

Trends Neurosci. 2019 Sep 5. pii:SS0166-2236(19)30159-6. doi: 10.1016/j.tins.2019.08.009. [Epub ahead of print]

PMID: 31495452 [PubMed - as supplied by publisher]

August Publication Round-Up!

Summer can be the slow season of research with labs taking the time to enjoy the Seattle sunshine and take those long overdue vacations. The publication list from CERID labs, PIs, and lab technicians say otherwise – 8 publications have hit the PubMed stands since the second week of August.

Read here!

Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type 1 and III Interferons.

Forero A, Ozarkar S, Li H, Lee CH, Hemann EA, Nadjsombati MS, Hendricks MR, So L, Green R, Roy CN, Sarkar SN, von Moltke K, Anderson SK, Gale M Jr, Savan R. 

Immunity. 2019 Aug 22. pii:S1074-7613(19)30323-1. doi: 10.1016/j.immuni.2019.07.007. [Epub ahead of print]

PMID: 31471108 [PubMed - as supplied by publisher] 

TOLLIP deficiency is associated with increased resistance to Legionella pneumophila pneumonia.

Shah JAEmery R, Lee B, Venkatasubramanian SSimmons JD, Brown M, Hung CF, Prins JM, Verbon A, Hawn TR, Skerrett SJ.  

Mucosal Immunol. 2019 Aug 28. doi:10.1038/s41385-019-0196-7. [Epub ahead of print]

PMID: 31462698 [PubMed - as supplied by publisher]

In Vitro Culture of Cryptosporidium parvum Using Hollow Fiber Bioreactor: Applications for Simultaneous Pharmacokinetic and Pharmacodynamic Evaluation of Test Compounds. 

Yarlett N, Morada M, Gobin M, Van Voorhis WArnold S

Methods Mol Biol. 2020;2052:335-350. doi: 10.1007/978-1-4939-9748-0_19. 

PMID: 31452171 [PubMed - in process]

Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Response to Live Toxigenic versus Heat-Inactivated Vibro cholerae.

Weil AA, Ellis CN, Debela MD, Bhuiyan TR, Rashu R, Bourque DL, Khan AI, Chowdhury F, LaRocque RC, Charles RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. 

mSphere. 2019 Aug 21;4(4). pii: e00206-19. doi:10.1128/mSphere.00206-19.

PMID: 31434744 [PubMed - in process]

Evaluating Respiratory Cryptosporidiosis in Pediatric Diarrheal Disease: Protocol for a Prospective, Observational Study in Malawi.

Nyangulu W, Van Voorhis W, Iroh Tam PY. 

BMC Infect Dis. 2019 Aug 19;19(1):728. doi 10.1186/s12879-019-4380-x.

PMID: 31426759 [PubMed - in process]

STING is required for host defense against neuropathological West Nile virus infection.


McGuckin Wuertz K, Treuting PM, Hemann EA, Esser-Nobis K, Snyder AG, Graham JB, Daniels BP, Wilkins C, Snyder JM, Voss KM, Oberst A, Lund J, Gale M Jr.


PLoS Pathog. 2019 Aug 15;15(8):e1007899. doi: 10.1371/journal.ppat.1007899. eCollection 2019 Aug.


PMID: 31415679 [PubMed - in process]

Risk of Zika Microencephaly Correlates with Features of Maternal Antibodies

Robbiani DF, Olsen PC, Costa F, Wang Q, Oliveira TY, Nery N Jr, Aromolaran A, do Rosário MS, Sacramento GA, Cruz JS, Khouri R, Wunder EA Jr, Mattos A, de Paula Freitas B, Sarno M, Archanjo G, Daltro D, Carvalho GBS, Pimentel K, de Siqueira IC, de Almeida JRM, Henriques DF, Lima JA, Vasconcelos PFC, Schaefer-Babajew D, Azzopardi SA, Bozzacco L, Gazumyan A, Belfort R Jr, Alcântara AP, Carvalho G, Moreira L, Araujo K, Reis MG, Keesler RI, Coffey LL, Tisoncik-Go J, Gale M Jr, Rajagopal L, Adams Waldorf KM, Dudley DM, Simmons HA, Mejia A, O'Connor DH, Steinbach RJ, Haese N, Smith J, Lewis A, Colgin L, Roberts V, Frias A, Kelleher M, Hirsch A, Streblow DN, Rice CM, MacDonald MR, de Almeida ARP, Van Rompay KKA, Ko AI, Nussenzweig MC.


J Exp Med. 2019 Aug 14. pii: jem.20191061. doi: 10.1084/jem.20191061. [Epub ahead of print]


PMID: 31413072 [PubMed - as supplied by publisher]

RIG-I-like Receptors Direct Infammatory Macrophage Polarization against West Nile Virus Infection

Stone AEL, Green R, Wilkins C, Hermann Ea, Gale M Jr

Nat Commun. 2019 Aug 13; 10(1):3649. doi: 10.1038/s414 67-019-11250-5

PMID: 31409781[PubMed - in process]. 

Human CD4+ T cells Specific for Merkel Cell Polyomavirus Localize to Merkel cell Carcinomas and Target a Required Oncogenic Domain

Longino NV, Yang J, Iyer JG, Ibrani D, Chow IT, Laing KJCampbell VL, Paulson KG, Kulikauskas RM, Church CD, James EA, Ngheim P, Kwok WW, Koelle DM

Cancer Immunol Res. 2019 Aug 12. pii:canimm.0103.2019. doi: 10.1158/2326-6066.CIR-19-0103. [Epub ahead of print]

PMID: 31405946 [PubMed - as supplied by publisher] 


Interleukin-6 Improves Infection Identification when Added to Physician Judgment During Evaluation of Potentially Setptic Patients

Henning DJ, Hall MK, Watsjold BK, Bhatraju PK, Kosamo S, Shapiro NI, Liles WC, Wurfel MM.

Am J Emerg Med. 2019 Jul 25:158361. doi: 10.1016/j.ajem.2019.158361. [Epub ahead of print] 

PMID: 31375355 [PubMed - as supplied by publisher]  

Physician Judgment and Circulating Biomarkers Predict 28-Day Mortality in Emergency Department Patients 

Henning DJ, Bhatraju PK, Johnson NJ, Kosamo S, Shapiro NI, Zelnick ZR, Liles WC, Wurfel MM.

Crit Care Med.. 2019 Aug 1. doi: 10.1097/CCM.0000000000003899. [Epub ahead of print]

PMID: 31369425 [PubMed - as supplied by publisher]  

Nutrition support for HIV-TB co-infected adults in Senegal, West Africa: A Randomized Pilot Implementation Study 

Benzekri NA, Sambou JF, Tamba IT, Diatta JPSall I, Cisse O, Thiam M, Bassene G, Badji NM, Faye KSall FMalomar JJSeydi MGottlieb GS

PLoS One. 2019 Jul 18;14(7):e0219118. doi: 10.1371/journal.pone.0219118. eCollection 2019.

PMID: 31318879 [PubMed - in process] 

Traditional healers, HIV outcomes, and mortality among people living with HIV in Senegal, West Africa

Benzekri NA, Sambou JF, Ndong S, Tamba IT, Faye DDiallo MBDiatta JP, Faye KSall ISall FMalomar JJHawes SESeydi MGottlieb GS, UW-Senegal Research Collaboration.

AIDS. 2019 Jul 15; 33(9):1521-1526. doi:10.1097/QAD.0000000000002232.


Dr. Noelle Benzekri CFAR New Investigator Award Recipient

CERID investigator Dr. Noelle Benzekri has been awarded the CFAR New Investigator Award to continue her research stemming from her July publication in AIDS: “Traditional healers, HIV outcomes, and mortality among people living with HIV in Senegal, West Africa.” Read more about the award, her work and publication here!

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HIV-2 infection in Senegal: virological failures and resistance to antiretroviral drugs (ARVs).

Ba S, Dia-Badiane NM, Hawes SE, Deguenonvo LF, Sall F, Ndour CT, Faye K, Traoré F, Touré M, Sy MPRaugi DNKiviat NBSmith RA, Seydi MSow PSGottlieb GS.


Pan Afr Med J. 2019 Jul 18;33:222. doi: 10.11604/pamj.2019.33.222.15771. eCollection 2019. French.


PMID: 31692792 [PubMed - in process]

Models to Predict the Public Health Impact of Vaccine Resistance: A Systematic Review

Reid MC, Peebles K, Stansfield SE, Goodreau SM, Abernethy N, Gottlieb GS, Mittler JE, Herbeck JT. 

Vaccine. 2019 Jul 12. pii: S0264-410X(19)30891-6. doi: 10.1016/j.vaccine.2019.07.013 [Epub ahead of print] Review.

PMID: 31307874 [PubMed - as supplied by publisher] 


Understanding How BCG Vaccine Protects Against Mycobacterium tuberculosis Infection: Lessons From Household Contact Studies. 

Lalvani A, Seshadri C.

J Infect Dis. 2019 Jul 12. pii:jiz261. doi: 10.1093/infdis/jiz261. [Epub ahead of print] no abstract available.

PMID: 31298279

The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections. 

Bender AM, Simonetti FR, Kumar MR, Fray EJ, Bruner KM, Timmons AE, Tai KY, Jenike KM, Antar AAR, Liu PT, Ho YC, Raugi DNSeydi MGottlieb GS, Okoye AA, Del Prete GQ, Picker LJ, Mankowski JL, Lifson JD, Siliciano JD, Laird GM, Barouch DH, Clements JE, Siliciano RF.

Cell Host Microbe. 2019 Jul 10; 26(1):73-85.e4. doi: 10.106/j.chom.2019.06.005

PMID: 31295427  [PubMed - in process]