This is unpublished

Frederick S.
Buckner
MD

Frederick S. Buckner

(206) 616-9214

750 Republican Street, Room E631, Seattle, WA 98109

Faculty
Pinned
Academic
Professor Department of Medicine, Division of Allergy and Infectious Diseases

Biography

Dr. Buckner's research is focused on the discovery of antimicrobial agents, including antiparasitic and antibacterial drugs. 

He works in the arena of preclinical research including target identification/validation, compound screening, pharmacology and small-animal efficacy models.

Education & Training: 

BA Princeton University Princeton NJ (1979-1983)

MD University of Washington Seattle WA (1984-1988)

Intern/Residency University of Minnesota Minneapolis, MN (1988-1991)

Chief Resident, Minneapolis Veterans Administration Medical Center Minneapolis MN (1991-1992)

Infectious Diseases Fellowship University of Washington Seattle WA (1992-1995)

Honors: 

Magna Cum Laude, Princeton University (1983)

Graduation with Honors, University of Washington Medical School (1988)

Philip and Helen Fialkow Scholar, University of Washington (2004)

Science in Medicine Lectureship, University of Washington (2012)

President, Western Society for Clinical Investigation (2015)

Alpha Omega Alpha Honor Medical Society (2018)

Related Links

Buckner Lab

Publications

PubMed Publications

 

Buckner FS, Ranade RM, Gillespie JR, Shibata S, Hulverson MA, Zhang Z, Huang W, Choi R, Verlinde CLMJ, Hol WGJ, Ochida A, Akao Y, Choy RKM, Van Voorhis WC, Arnold SLM, Jumani RS, Huston CD, Fan E. Optimization of Methionyl tRNA-Synthetase Inhibitors for Treatment of Cryptosporidium Infection. Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02061-18. doi: 10.1128/AAC.02061-18. Print 2019 Apr. PubMed PMID: 30745384.

Nagendar P, Gillespie JR, Herbst ZM, Ranade RM, Molasky NMR, Faghih O, Turner RM, Gelb MH, Buckner FS. Triazolopyrimidines and Imidazopyridines: Structure-Activity Relationships and in Vivo Efficacy for Trypanosomiasis. ACS Med Chem Lett. 2018 Dec 4;10(1):105-110. doi: 10.1021/acsmedchemlett.8b00498. eCollection 2019 Jan 10. PubMed PMID: 30655955; PubMed Central PMCID: PMC6331164.

Faghih O, Zhang Z, Ranade RM, Gillespie JR, Creason SA, Huang W, Shibata S, Barros-Álvarez X, Verlinde CLMJ, Hol WGJ, Fan E, Buckner FS. Development of Methionyl-tRNA Synthetase Inhibitors as Antibiotics for Gram-Positive Bacterial Infections. Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e00999-17. doi: 10.1128/AAC.00999-17. Print 2017 Nov. PubMed PMID: 28848016; PubMed Central PMCID: PMC5655057.

Patrick DA, Gillespie JR, McQueen J, Hulverson MA, Ranade RM, Creason SA, Herbst ZM, Gelb MH, Buckner FS, Tidwell RR. Urea Derivatives of 2-Aryl-benzothiazol-5-amines: A New Class of Potential Drugs for Human African Trypanosomiasis. J Med Chem. 2017 Feb 9;60(3):957-971. doi: 10.1021/acs.jmedchem.6b01163. Epub 2016 Dec 19. PubMed PMID: 27992217; PubMed Central PMCID: PMC5362113.