Chlamydial infection is a common sexually transmitted infection (STI) in humans caused by the bacterium Chlamydia trachomatis.
Chlamydia research at CERID is focused on deciphering the mechanisms by which Chlamydia trachomatis manipulates cellular function in order to exit host cells and cause infectious disease.
Gonorrhea is a sexually transmitted infection (STI) caused by infection with the Neisseria gonorrhoeae bacterium.
CERID is working to combat Neisseria resistance by developing novel drug leads through a structural-based drug design pipeline in collaboration with the Seattle Structural Genomics Center for Infectious Disease (SSGCID).
Leprosy & Non-Tuberculous Mycobacteria
Leprosy (also known as Hansen’s disease) is an infection caused by slow-growing bacteria called Mycobacterium leprae. Non-tuberculous mycobacteria are organisms found in soil and water that can infect the airways and lung tissue.
Mycoplasma genitalium is a bacterial infection that causes several sexually transmitted infections (STIs), such as urethritis in men and cervicitis in women.
CERID research includes structural genomic studies through the Van Voorhis’ lab’s affiliated project, Seattle Structural Genomics Center for Infectious Disease.
Pseudomonas infection is caused by strains of bacteria found widely in the environment; the most common type causing infections in humans is called Pseudomonas aeruginosa.
CERID is investigating immunologic mechanisms of disease pathogenesis with an emphasis on genetic, cellular and molecular studies of the human innate immune response.
Salmonellosis is an infection caused by consumption of foods containing Salmonella bacteria.
Shigellosis is an infectious disease caused by a group of bacteria called Shigella.
CERID is working to establish a mouse model of infection to allow for better understanding of clinical pathology and for the testing of new therapeutics.
Staphylococcus & Streptococcus
Staphylococcus and Streptococcus are genera of Gram-positive bacteria.
Tuberculosis (TB) is a common infectious bacterial disease caused by Mycobacterium tuberculosis.
TB research at CERID is focused on immune response to TB, pathogenesis, and vaccine development.